Overview of quantitative trait loci investigated in this study.

1The loci are named according to the first gene in the region of interest, starting at the 5′ end of the region.
2ROI = region of interest. Number of kb sequenced for the locus.
3Total Genes is the number of genes in the locus; Targeted Genes is the number of genes investigated in this study.
4Please see Table S3 for a complete listing of all variant sites, along with their MAF and annotation.
5Phenotype abbreviations: TC = total cholesterol, LDL-C = low density lipoprotein cholesterol, HDL-C = high density lipoprotein cholesterol, TG = triglycerides, FG = Fasting Glucose, FI = Fasting Insulin. Previous association evidence for lipid traits is from Kathiresan et al. 2008, Willer et al. 2008 and Teslovich et al. 2010; for glucose Dupuis et al. 2010, and for insulin Sabatti et al. 2009. The “array SNP” is the GWAS array-genotyped SNP (not sequence variant) with the smallest p-value to indicated traits in this study and is not necessarily the same SNP highlighted in previous studies.
6Array SNP MAF and p-values are taken from the current study.