IFNGR1
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资源简介：
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
该基因（IFNGR1）编码γ干扰素受体的配体结合链（α链）。人γ干扰素受体是由IFNGR1和IFNGR2组成的异源二聚体。IFNGR1基因中的遗传变异与幽门螺杆菌感染易感性相关。此外，IFNGR1的缺陷是孟德尔型结核病易感性的原因，亦称家族性播散性非典型分枝杆菌感染。[由RefSeq提供，2008年7月]
提供机构：
Rat Genome Database
