Background Anti-human leukocyte antigen donor-specific antibodies (anti-HLA DSAs) are recognized as a major barrier to patients’ access to organ transplantation and the major cause of graft failure. T
Background Acute allograft rejection (AAR) is an important cause of morbi mortality in heart transplant (HT) patients, particularly during the first year. Endomyocardial biopsy (EMB) is the “gold stan
BackgroundPre-transplant donor-specific anti-human leukocyte antigen antibody (HLA-DSA) is a recognized risk factor for acute antibody-mediated rejection (ABMR) and allograft failure. However, the cli
Non-permissive residues between patient and donor HLA antigens or alleles reported to have deleterious outcomes in HCT [45], [46], [47], [48]. The observed residues from all known HLA-A alleles at eac