Cryo-EM structure of siponimod -bound Sphingosine-1-phosphate receptor 5 in complex with Gi protein
收藏Protein Data Bank Japan2025-06-18 更新2026-03-21 收录
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Cryo-EM structure of siponimod -bound Sphingosine-1-phosphate receptor 5 in complex with Gi protein Descriptor: 1-[[4-[(~{E})-~{N}-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-~{C}-methyl-carbonimidoyl]-2-ethyl-phenyl]methyl]azetidine-3-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Yuan, Y, Jia, G.W, Shao, Z.H, Su, Z.M. Deposit date: 2021-05-24 Release date: 2021-09-29 Last modified: 2025-06-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition. Cell Res., 31, 2021
创建时间：
2021-05-24
