Cryptands with 1,3,5-Tris(1′,3′-dioxan-2′-yl)-benzene Units: Synthesis and Structural Investigations

Various
cryptands based on 1,3-dioxane decorated 1,3,5-trisubstituted-benzene
building blocks, connected by different chains (exhibiting ester,
ether, or triazol groups) to several units with C3 symmetry, are reported. The structure of the compounds
was investigated by single crystal X-ray diffraction, NMR, and MS.
The role of the 1,3-dioxane units was targeted to ensure the preorganization
of the substrate for the macrocyclization reactions on one side, and
for easier NMR assignment of the structure of the cryptands on the
other side.