Genome sequencing of engineered Streptomyces strains to understand actinophage integrase substrate specificity and accuracy and correlation between gene locations and heterologous gene expression leve
The study is aimed at identification and bioinformatic characterization of non-ribosomal biosynthetic pathways for bioactive compounds inducing cytotoxic effects or programmed cell death (apoptosis) i
Since the discovery of penicillin, natural products and their derivatives have been a valuable resource for drug discovery. With recent development of genome mining approaches in the post-genome era,
