The role of TEFM in mitochondrial gene expression [TruSeq]. Mus musculus
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资源简介：
We investigated the role of TEFM in vivo by creating heart- and skeletal-muscle specific knockout of this gene. We identified that TEFM is required for the processivity of POLRMT and its loss leads to significantly decreased mitochondrial transcription. Overall design: Total RNA from isolated heart mitochondria from four control mice (L/L) and four Tefm knockout mice (L/L, cre), was sequenced and analysed for differential expression.
创建时间：
2017-08-04
