Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor Descriptor: 2-{(2Z,5S)-4-hydroxy-2-[(2E)-(2-hydroxybenzylidene)hydrazinylidene]-2,5-dihydro-1,3-thiazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide, 2-{(5S)-2-[(2E)-2-(2-hydroxybenzylidene)hydrazinyl]-4-oxo-4,5-dihydro-1,3-thiazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide, SULFATE ION, ... Authors: Tochowicz, A, Finer-Moore, J, Stroud, R.M, Costi, M.P. Deposit date: 2012-03-07 Release date: 2012-11-14 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.302 Å) Cite: Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase. J.Med.Chem., 55, 2012
创建时间：
2012-03-07
