Univariate and multivariate survival analyses individual markers.

Shown are the results of the univariate and multivariate analyses of all individual markers, with all p-values and hazard ratios (HR) and their 95% confidence intervals (95% CI). The "low expression" group was used as the reference group. Covariates included in all multivariate analyses were age at operation, gender, TNM tumor stage, tumor location, tumor size, microsatellite stability (MSS) status, tumor in the follow up and adjuvant therapy. OS = overall survival, DSS = disease-specific survival, LRRFS = locoregional recurrence-free survival, DRFS = distant recurrence- free survival. Significant p-values are indicated in bold, p-values showing a trend (0.05≤0.1) in Italic. Univariate and multivariate survival analyses individual markers.