Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog

NIAID Data Ecosystem2026-05-01 收录

DNA损伤修复

结构生物学

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Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog

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2023-10-18

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

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Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

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LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE Descriptor: 5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID, LUMAZINE SYNTHASE Authors: Meining, W, Mortl, S, Fischer, M, Cush

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蛋白质晶体学

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The Finnish BAG encompasses 24 groups active in crystallography in Finland. The projects vary widely and include membrane proteins and protein complexes, other proteins involved...

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Escherichia coli polynucleotide phosphorylase in complex with recognition site of RNase E

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Escherichia coli polynucleotide phosphorylase in complex with recognition site of RNase E Descriptor: Polyribonucleotide nucleotidyltransferase, Ribonuclease E Authors: Paris, G, Luisi, B.F. Deposit d

Protein Data Bank Japan2025-11-05 更新20

Structural studies of proteins and protein complexes involved in regulation, ...

蛋白质结构解析

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Our BAG is focussed around a large group of experimenters who work on a diverse range of biological and physical problems. Whilst this makes it difficult to write an overall...

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Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog

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