SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE164628
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资源简介：
Transcriptomic profiling by high-throughput sequencing of primary human Beta cells following SIX2 or SIX3 loss of function. SIX2 genome-binding profiling by CUT&RUN and high-throughput sequencing. This SuperSeries is composed of the SubSeries listed below. Profiling FACS-purified human pancreatic SIX2 or SIX3 shRNA-mediated knockdown GFP+ Beta cells by RNA-Seq, compared to a non-targeting shRNA control/donor. We analyzed the genomic targets of SIX2 by SIX2-Flag overexpression and CUT&RUN compared to a non-antibody control. Refer to individual Series
创建时间：
2021-01-31
