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FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development

ChEBI2015-06-17 更新2026-07-12 收录

卵巢颗粒细胞瘤

癌症基因功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-67662 数据链接链接失效反馈

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FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development

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创建时间：

2015-06-17

癌症基因功能

卵巢癌分子机制

Ubiquitination-directed protein degradation is important for tumor initiation and maintenance in many cancers. E3 ligases containing HECT domains are emerging as new therapeutic targets. In contrast t

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The study of SWELL1 in liver cancer

癌症基因功能

SWELL1分子通路

To obtain unbiased insight into putative SWELL1-dependent molecular pathways in cancer, RNA-sequencing analysis was performed using si-RNA in human hepatoma cell lines HepG2, compared with si-control

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RNA-Seq of FBXO44 knockdown in MDA-MB-231. RNA-Seq of FBXO44 knockdown in MDA-MB-231

癌症基因功能

抗病毒信号通路

Targeting FBXO44 or SUV39H1 transcriptionally reactivates repetitive elements, triggering RIG-I-MDA5-MAVS and cGAS-STING antiviral defense responses and IFN signaling, specifically in cancer cells Ove

NIAID Data Ecosystem20

The whole transcriptome expression profiling comparison between the CtBP1 knockdown, CtBP2 knockdown and scramble control in ovarian cancer SKOV3 cells

癌症基因功能

转录组分析

To discover the core gene expression features of CtBP1, CtBP2 differently regulated in ovarian cancer SKOV3 cells. The compared the whole transcript expression profiling between CtBP1 knockdown, CtBP2

NIAID Data Ecosystem30

FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development. Mus musculus

卵巢颗粒细胞瘤

生殖肿瘤分子机制

The Forkhead Box, FOXO1 and FOXO3, transcription factors regulate multiple functions in mammalian cells. Selective inactivation of the Foxo1 and Foxo3 genes in murine ovarian granulosa cells severely

NIAID Data Ecosystem20

FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development

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