Association results on Kosrae for select previously known, associated loci.

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For SNPs not directly genotyped on the Affymetrix array (n = 9), association results are reported for a proxy on the Affymetrix chip with strong correlation (r2≥0.95) to the original SNP in both HapMap Caucasian and Asian populations. The effect size (β) is expressed as the number of standard deviations change in phenotype for each copy of the associated allele. “Phet β” denotes p-values for the test of heterogeneity between the Caucasian and Kosrae effect sizes. SNPs with low frequency in Kosraens (MAF<0.05; n = 6) were omitted from the test of heterogeneity for effect sizes. “Phet Freq”denotes p-values for similarity between frequency of the risk allele in Caucasians and Kosraens. SNPs not directly genotyped on the Affymetrix array were omitted from the comparison of allele frequencies. “−,” not analyzed.