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HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs [differentiated SH-5Y cells]

ChEBI2013-01-17 更新2026-07-21 收录

HIV相关神经认知障碍机制

microRNA调控与神经元功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43534 数据链接链接失效反馈

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资源简介：

HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs [differentiated SH-5Y cells]

应用场景：

创建时间：

2013-01-17

HIV相关神经认知障碍机制

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CCR5 controls neuronal damage in an in vivo model of HIV glycoprotein 120-induced brain injury. Mus musculus

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The chemokine receptor CCR5 is a major co-receptor for human immunodeficiency virus 1 (HIV-1) mediating infection of target cells1,2. Beyond its function as co-receptor, CCR5 also influences the cours

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Data_Sheet_1_Reversal of Cognitive Impairment in gp120 Transgenic Mice by the Removal of the p75 Neurotrophin Receptor.PDF

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p75神经营养因子受体

Activation of the p75 neurotrophin receptor (p75NTR), by the proneurotrophin brain-derived neurotrophic factor (proBDNF), triggers loss of synapses and promotes neuronal death. These pathological feat

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MicroRNA profiling of Basal ganglia tissue from chronically SIV infected rhesus macaques II

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The study describes miRNA expression changes in basal ganglia (BG) of chronically SIV-infected rhesus macaques. HIV/SIV-associated neurological disorder (HAND) represents a major comorbidity affecting

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Modeling HIV-1 Induced Neuroinflammation in Mice: Role of Platelets in Mediating Blood-Brain Barrier Dysfunction

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The number of HIV-1 positive individuals developing some form of HIV-associated neurocognitive disorder (HAND) is increasing. In these individuals, the integrity of the blood-brain barrier (BBB) is co

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HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs [differentiated SH-5Y cells]

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