Neutralizing antibodies induced by recombinant EMC viruses in mice.
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a Eight-week-old male BALB/c mice (n = 5) were intraperitoneally immunized with 5×104 PFU recombinant virus and T1100I in 0.2 ml 2% DMEM. Mice (n = 3) inoculated with 0.2 ml 2% DMEM in the same route were used as negative control.
b Neutralization antibody titers were defined as the reciprocal of highest serum dilution that neutralized 100 TCID50 of JXwn06 and were expressed as the geometric mean value of 5 mice.
c Neutralization antibody titers were defined as the reciprocal of highest serum dilution that neutralized 200 TCID50 of CSFV C-strain and were expressed as the geometric mean value of 5 mice.
d Serum samples were collected at day 0 before immunization.
e Mice were boosted with identical dose (5×104 PFU) of either viruses or medium at 14 dpi.
Neutralizing antibodies induced by recombinant EMC viruses in mice.
创建时间:
2015-06-15



