Neutralizing antibodies induced by recombinant EMC viruses in mice.
收藏资源简介：
a Eight-week-old male BALB/c mice (n = 5) were intraperitoneally immunized with 5×104 PFU recombinant virus and T1100I in 0.2 ml 2% DMEM. Mice (n = 3) inoculated with 0.2 ml 2% DMEM in the same route were used as negative control. b Neutralization antibody titers were defined as the reciprocal of highest serum dilution that neutralized 100 TCID50 of JXwn06 and were expressed as the geometric mean value of 5 mice. c Neutralization antibody titers were defined as the reciprocal of highest serum dilution that neutralized 200 TCID50 of CSFV C-strain and were expressed as the geometric mean value of 5 mice. d Serum samples were collected at day 0 before immunization. e Mice were boosted with identical dose (5×104 PFU) of either viruses or medium at 14 dpi. Neutralizing antibodies induced by recombinant EMC viruses in mice.
