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The Renin-Angiotensin System, High Inherent Aerobic Capacity, and Low Breast Cancer Risk

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Conclusions: This study found a biologically plausible heritable relationship linking mechanisms associated with aerobic capacity and the development of breast cancer. Through RNA-seq analyses, we identified AGT as a biomarker pointing to differences in the regulation of RAS as a candidate mediator linking aerobic capacity and breast cancer.

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