Optimization of genetically encoded GABA indicator
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The GENIE Project Team at HHMI Janelia has developed a second-generation genetically encoded GABA indicator (Fig. 1a), in collaboration with Jonathan Marvin and Loren Looger. The sensor is based on iGABASnFR (Marvin, J.S., Shimoda, Y., Magloire, V. et al. A genetically encoded fluorescent sensor for in vivo imaging of GABA. Nat Methods 16, 763–770 (2019). https://doi.org/10.1038/s41592-019-0471-2), and has the following features, tested extensively in cultured neurons.
创建时间:
2022-05-05



