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Whole-genome sequencing in gastric cancer (part2)

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NIAID Data Ecosystem2026-03-14 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001006575
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we analysis structural variations (SVs) and mutational signatures via whole-genome sequencing of 168 GCs. Our data demonstrates diverse models of complex SVs operative in GC, which lead to high-level amplification of oncogenes. We find varying proportion of tandem-duplications (TDs) among individuals and identify 24 TD hotspots involving well-established cancer genes such as CCND1, ERBB2 and MYC.EGA study EGAS00001006575
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2022-11-02
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