Transcriptome dataset of human corneal endothelium. Homo sapiens

A transcriptome dataset from ribosomal RNA-depleted total RNA of corneal endothelium from the eyes derived from seven Caucasians without ocular diseases. As corneal endothelium, which is one of the five different layers of cornea, has limited proliferative capacity, damage to corneal endothelium by multiple pathological conditions, such as Fuchs endothelial corneal dystrophy (FECD; OMIM ID: 204870), invasive cataract surgery, glaucoma surgery, and endotheliitis, induce loss of corneal transparency resulting in severe visual disturbance. Therofore, the dataset should be useful for investigating the function/dysfunction of cornea as well as for the extended transcriptome analyses integrated with the data of non-coding RNAs.