Data is in comma-separated value (csv) format. Column definitions: variant: the name of the plasmid variant used for the cytometry measurements; mutation_codes: a list of amino acid substit

NIAID Data Ecosystem10

Binding affinities of double mutants for MD2.

蛋白质亲和力

突变与病变效应分析

Fold-increase indicates the ratio of binding affinities between the mutants and wild-type decoy receptor.

NIAID Data Ecosystem20

Mutational probability of affinity increase and affinity decrease.

突变与病变效应分析

亲和力变化模拟

#number of segregating mutations of each class among the 6 sim lines;*chi-square test p-value is based on 10,000 simulations as one of the cells contain less than 5 counts.

Figshare2015-12-02 更新10

S. enterica HisA mutant - D10G, G11D, dup13-15, G44E, G102A

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