CUT&RUN analysis of murine wt NPCs grown in alone and in co-culture with primary brain microvascular endothelial cells

We previously established co-culture assay in which NPCs acquire phenotypic hallmarks of quiescence upon direct cell-cell contact with primary brain microvascular endothelial cells (bmvEC). Here, we used this in vitro assay to identify the mechanisms by which p53 enforces quiescence Overall design: The experiment was conducted to identify the direct binding sites of p53 at response elements upon co-culture-induced quiescence in mouse NPCs