Gene expression changes in lung adenocarcinoma cells from overexpression of p53-regulated tumor-suppressive lncRNA (PTSL)

RNA-sequencing was performed to evaluate gene expression changes following ectopic expression of PTSL or vector control in lung adenocarcinoma cells. Genes and pathways that induce proliferation were reduced with elevated levels of PTSL. Overall design: From RNA-sequencing gene expression profiles were generated in PTSL-expressing lung adenocarcinoma cells and control lung adenocarcinoma cells.