High-throughput quantitation of serological ceramides/dihydroceramides by LC/MS/MS
收藏DataCite Commons2022-12-21 更新2025-05-17 收录
下载链接:
https://www.immport.org/shared/study/SDY1692
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资源简介:
The study developed the LC/MS/MS assay to quantify 16 ceramides and 10 dihydroceramides in human serum within 5 minutes. Validated the assay results against a set of quality criteria in FDA guidelines: Lower Limit of Quantitation (1 nM), linearity (R2>0.99), precision (imprecision<15 %), accuracy (inaccuracy<15 %), extraction recovery (>90 %), stability (>85 %), and carryover (<0.01 %). With enhanced sensitivity and specificity, the study established gestation baselines of ceramides and dihydroceramides in pregnancy
提供机构:
ImmPort
创建时间:
2020-12-10



