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Loss of Foxp3-driven epigenetic modification leads to regulatory T cell insufficiency

ChEBI2012-12-07 更新2026-07-21 收录

细胞免疫调控

表观遗传

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35164 数据链接链接失效反馈

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Loss of Foxp3-driven epigenetic modification leads to regulatory T cell insufficiency

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创建时间：

2012-12-07

细胞免疫调控

FGF信号通路

Natural killer (NK) cells are lymphocytes of the innate immune system that are involved in controlling tumors or microbial infections through the production of interferon gamma (IFN-γ). Granulocyte-co

NIAID Data Ecosystem110

TSLP administration promotes homeostatic maturation of human cDC2

细胞免疫调控

树突状细胞成熟

To test whether TSLP triggers the homeostatic maturation program of human splenic cDC2 (DC2hm program) in vitro, we administrated TSLP to in-culture human splenic cDC2 and performed RNA-seq. The resul

NIAID Data Ecosystem50

Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.

转录调控

表观遗传

The conserved core domain of the TATA binding protein (TBP) interacts with multiple partners forming the complexes required for transcription by RNA Polymerases I, II and III. We use genetically modif

NIAID Data Ecosystem50

8p H3K27me3 Part 2

表观遗传

X染色体失活

Green is RNA FISH using a probe against XIST RNA. Red is an anti-H3K27me3 antibody. Blue is DAPI. These images were used to calculate data shown in Table 2.

Figshare2016-01-20 更新80

Whole-genome DNA methylation maps for human and chimpanzee peripheral blood leukocytes (PBLs).

跨物种DNA甲基化分析

表观遗传

It has been thought that epigenetic changes underlie the evolutionary divergence of phenotype between closely related species. To study differences in DNA methylation between humans and chimanzees, we

NIAID Data Ecosystem50

Loss of Foxp3-driven epigenetic modification leads to regulatory T cell insufficiency

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