ITK kinase domain with compound 27 (N-{1-[(1R)-3-(DIMETHYLAMINO)-1-PHENYLPROPYL]-1H-PYRAZOL-4-YL}-6-(1H-PYRAZOL-4-YL)-1H-INDAZOLE-3-CARBOXAMIDE)
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4ppc
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资源简介：
ITK kinase domain with compound 27 (N-{1-[(1R)-3-(DIMETHYLAMINO)-1-PHENYLPROPYL]-1H-PYRAZOL-4-YL}-6-(1H-PYRAZOL-4-YL)-1H-INDAZOLE-3-CARBOXAMIDE) Descriptor: N-{1-[(1R)-3-(dimethylamino)-1-phenylpropyl]-1H-pyrazol-4-yl}-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK Authors: Eigenbrot, C, Shia, S. Deposit date: 2014-02-26 Release date: 2014-06-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
创建时间：
2014-02-26
