Additional file 5 of Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study

Additional file 5. Original data of average biomarker levels underlying heatmap presentation. Displayed are average biomarker levels in all subjects, that were adapted to the kit detection limits, in descending order of adapted arbitrary unit (AAU). For the calculation of the AAU, the mean arbitrary unit (AU) for parametric datasets or the median AU for non-parametric datasets was multiplied by the minimum detection level (pg/mL) of each protein, that was given by the certificate of analysis of each kit. Underlined proteins were parametric. Proteins were separated according to the magnitude of AAU levels. An AAU ≥ 10*105 was labelled as a high level, 10*105 > AAU ≥ 1*103 as a medium level and AAU < 1*103 as a low level. Some proteins included in the low level group showed probands with MFI values of zero below the detection limit. Since most probands exhibited values that exceeded the detection limit, these specific proteins were not excluded, but included in the low biomarker level group.