BackgroundThe role of Eph receptors and related ephrin (EFN) ligands (as the largest family of transmembrane-bound RTKs) in immunomodulation in many types of cancer, especially bladder cancer (BLCA),

NIAID Data Ecosystem30

Lack of Fzd6 in Ciliated Cells Suppresses Ferroptotic Alveolar Cell Death induced by LPS and Corona Virus [RNA-seq subset II]

肺部炎症机制

铁死亡调控

Pulmonary inflammation compromises lung barrier function and underlies many lung diseases including acute lung injury and acute respiratory distress syndrome (ARDS). However, mechanisms by which lung

NIAID Data Ecosystem20

PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

肿瘤抑制机制

铁死亡调控

The tumor suppressor protein p53 suppresses cancer by regulating processes such as apoptosis, cell cycle arrest, senescence, and ferroptosis. Whereas numerous p53 target genes have been identified, o

NIAID Data Ecosystem50

ETV4 transcriptionally activates STAT6 to inhibit ferroptosis and promote immune escape in thyroid cancer

免疫逃逸机制

铁死亡调控

Thyroid cancer (THCA) is one of the most common endocrine malignancies, with a significant increase in incidence over the past few decades. ETS variant transcription factor 4 (ETV4) is a member of the

NIAID Data Ecosystem30

Supplementary Table S1 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy

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