Supplementary materials: Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery

<b>These are peer-reviewed supplementary materials for the article '</b><b>Meta-analysis of visual pretreatment for </b><b>the prevention of emergence delirium in </b><b>children undergoing ophthalmic surgery</b><b>' published in the</b><b> </b><b><i>Journal of Comparative Effectiveness Research</i></b><b>.</b><b>Search strategy of Pubmed</b><b>Search strategy of Embase</b><b>Search strategy of Cochrane library</b><b>Search strategy of CNKI</b><b>Objective:</b> To evaluate the role of visual pretreatment in preventing emergence delirium in children receiving ophthalmic surgery. <b>Methods:</b> Four randomized controlled trials were identified in four databases, and a meta-analysis was conducted using RevMan 5.3. <b>Results:</b> Themeta-analysis demonstrated a significantly lower incidence of postoperative emergence delirium (risk ratio: 0.39; 95% CI: 0.31–0.49) and propofol rescue (risk ratio: 0.29; 95% CI: 0.13–0.65) but comparable modified Yale Preoperative Anxiety Scale score (mean difference: -3.66; 95% CI: -9.96 to 2.65) and incidence of adverse events in the visual pretreatment group. <b>Conclusion:</b> Visual pretreatment is effective in preventing postoperative emergence delirium in children undergoing ophthalmic surgery without significant adverse effects and can also decrease the incidence of propofol rescue.