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Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor SH-5

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor SH-5 Descriptor: (phenylmethyl) N-[(2S)-1-[[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]carbamate, 3C-like proteinase Authors: Senda, M, Konno, S, Hayashi, Y, Senda, T. Deposit date: 2021-02-01 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.15 Å) Cite: 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022

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2021-02-01
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