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Generation of an in vitro 3D Engineered Colorectal Cancer Patient-Derived Xenograft Model

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE151069
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资源简介:
We report on the development of an vitro model of colorectal cancer using cells isolated from a patient-derived xengraft (PDX) tumor. Transcriptome profiling was performed to compare molecular characteristics of in vitro 3D engineered CRC tissues to in vivo tumors. mRNA profiles of 3D engineered CRC tissues cultured for 15 days and the corresponding in vivo PDX subcutaneous tumor grown in NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NOD-SCID) mice.
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2020-05-23
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