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Mouse microglia express unique miRNA-mRNA networks to facilitate age-specific functions in the developing central nervous system [smRNA-seq]

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the expression of miRNA/mRNA regulatory networks in a developmental cohort of C57Bl/6 mice. This submission is the miRNA sequencing dataset. Overall design: Sequenced the miRNAome and mRNAome of primary mouse microglia during brain development and adult homeostasis (three age groups; P6, P15 and 8 weeks). Sequenced and compared small RNA expression in both CD45+ microglial cells and CD45- bulk CNS cells in each sample. mRNA expression was sequenced in CD45+ microglial cells.

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2023-05-26
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