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Single Nuclear RNAseq and MultiOme of IPF and Control Lung Tissue

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NIAID Data Ecosystem2026-05-02 收录
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Differentially affected regions of Idiopathic Pulmonary Fibrosis (IPF) lungs were assessed for changes in cell composition, gene expression and chromatin accessibility. Overall design: Frozen tissue cores from IPF lungs following transplant and unused donor control lungs were analyzed by microCT as previously described (PMID:22029978, PMID:31600171). Nuclei were isolated from frozen tissue and profiled with either snRNAseq or assays of paired snRNAseq and snATACseq data.

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2025-07-31
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