The effect of gene perturbation on the histone mark H3K27ac was evaluated in human Cas9 expressing MDA-MB231 cancers Human pancreatic cancer cell lines were cultured in DMEM supplemented with 10% feta
We report chromatin accessibility time-course profiling (ATAC-seq) of induced trophoblast stem cells (iTSCs) derived directly from human fibroblasts and naïve reprogramming intermediates. Overall des
A genome-wide screening identified effector genes of chromatin accessibility. To investigate the functional consequences of the loss of each effector gene, we conducted Mnase-seq with eHAP cells knock
