Crystal structure of PDE5A in complex with its inhibitor
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Crystal structure of PDE5A in complex with its inhibitor Descriptor: 5,6-diethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... Authors: Ren, J, Chen, T.T, Xu, Y.C. Deposit date: 2012-07-13 Release date: 2013-06-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5. J.Med.Chem., 55, 2012
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2012-07-13
