Hyperglycemia ischemic stroke patients

Hyperglycemia occurs in approximately 50% of acute ischemic stroke (AIS) patients, whether they are affected with diabetes or not, and is associated with an adverse prognosis. The current treatment of hyperglycemia with insulin and hypoglycemic drugs has not significantly improved the prognosis of patients, indicating that the mechanism of stroke-induced hyperglycemia is unclear. Therefore, this study aimed to investigate novel biomarkers involved in the mechanism of unfavorable prognosis in post-stroke hyperglycemia patients. During the screening stage, 20 consecutive ischemic stroke patients were enrolled between October and December 2020, in accordance with the budgetary constraints of this study. Of these, 10 ischemic stroke patients without hyperglycemia and 7 with hyperglycemia were met the criteria for sequencing.