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Streptococcus pyogenes strain:M75 Genome sequencing

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NIAID Data Ecosystem2026-04-25 收录
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A multifaceted characterisation of a controlled human infection model candidate strain, M75 611024, compared to two other GAS strains: GAS M12 611025, and CDC SS-496, an M1 strain administered to 88 subjects in 1970s pharyngitis controlled human infection model studies ('SS-496'). This study provides the rationale for the initial deployment of M75 611025 in a modern controlled human infection model, with the aim of safely and successfully causing pharyngitis in healthy adult volunteers.

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2020-08-25
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