Targeted Next-Generation Sequencing-Based Analysis of the Age-Related Microbial diversity and Antibiotic Resistance Genes in the Lower Respiratory Tract Infections patients

Lower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality. The lung microbiome represents an important reservoir for exchange of antimicrobial resistance genes. The pathogenic microbes remain not well understood among different age groups including children, youth, middle age and older.