Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responses
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https://www.ncbi.nlm.nih.gov/sra/SRP497018
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资源简介：
scRNA-seq analysis of patient-derived xenografts (PDX) in immunocompromised mice transfected by an intratumorally injected lipid nanoparticle carrying the reporter mRNA encoding for aVHH revealed that an optimized lipid nanoparticle, LNP-IT, transfected malignant cell types of HNSCC tumors and upregulated RNA and protein metabolic pathways.
创建时间：
2025-03-14
