Crystal structure of XIAP-BIR2 domain complexed with ligand bound
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Crystal structure of XIAP-BIR2 domain complexed with ligand bound Descriptor: 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, E3 ubiquitin-protein ligase XIAP, ZINC ION Authors: Pokross, M.E. Deposit date: 2014-11-07 Release date: 2015-03-04 Last modified: 2025-04-02 Method: X-RAY DIFFRACTION (1.96 Å) Cite: The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity. J.Med.Chem., 58, 2015
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2014-11-07
