BackgroundThe mammalian target of rapamycin (mTOR) is an evolutionarily conserved Ser/Thr protein kinase that plays a pivotal role in multiple fundamental biological processes, including synaptic plas
Metabolic stress and the increased production of reactive oxygen species (ROS) are two main contributors to neuronal damage and synaptic plasticity in acute ischemic stroke (AIS). The superoxide scave
RNA metabolism involves complex and regulated processes, some of which include transcription, intracellular transport, translation, and degradation. The involvement of RNA binding proteins in these pr
For short-time scale, instantaneous change of postsynaptic [Ca2+]i is α and its average over a long time is β. The difference (α−β) integrated over a short time (∫(α−β)dt) indicates whether the CF act
