SOS1 in Complex with Inhibitor BI-68BS
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SOS1 in Complex with Inhibitor BI-68BS Descriptor: 6,7-dimethoxy-~{N}-[(1~{R})-1-phenylethyl]quinazolin-4-amine, IMIDAZOLE, Son of sevenless homolog 1 Authors: Kessler, D, Fischer, G, Ramharter, J. Deposit date: 2019-08-02 Release date: 2020-08-26 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.917 Å) Cite: BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition. Cancer Discov, 11, 2021
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2019-08-02
