IGF1

ENCODES a protein that exhibits hormone activity (ortholog); insulin-like growth factor receptor binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN positive regulation of cell population proliferation; activation of protein kinase B activity (ortholog); androgen receptor signaling pathway (ortholog); PARTICIPATES IN altered insulin-like growth factor signaling pathway; cardiovascular system disease pathway; ceramide signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acromegaly (ortholog); acute kidney failure (ortholog); FOUND IN plasma membrane; alphav-beta3 integrin-IGF-1-IGF1R complex (ortholog); exocytic vesicle (ortholog); INTERACTS WITH 17beta-estradiol; bis(2-chloroethyl) sulfide; bisphenol A

编码一种表现出激素活性的蛋白质（同源物）；胰岛素样生长因子受体结合（同源物）；蛋白丝氨酸/苏氨酸激酶激活剂活性（同源物）；参与调控细胞群体增殖的正向调节；蛋白激酶B活性激活（同源物）；与雄激素受体信号通路（同源物）相关；参与改变胰岛素样生长因子信号通路；心血管系统疾病通路；鞘脂信号通路；与听神经瘤（同源物）、肢端肥大症（同源物）、急性肾功能衰竭（同源物）相关；存在于质膜中；alphav-beta3整合素-IGF-1-IGF1R复合物（同源物）；胞吐小泡（同源物）；与17β-雌二醇、二(2-氯乙基)硫化物、双酚A相互作用。