Identification of mitochondria-related action targets of quercetin in melanoma B16 cells

Quercetin can effectively inhibit tumor growth in various tumors. However, the exact action mechanisms of quercetin against melanoma have not been comprehensively clarified, which limits the application of quercetin. Accumulating evidence has suggested that the dysfunction of mitochondria is closely linked to carcinogenesis, a better understanding of the regulation of mitochondria-related genes will shed light on providing new therapies for melanoma. In this study, we performed RNA-seq from melanoma B16 cells treated with quercetin versus controls and screened for differentially expressed genes (DEGs).