Cediranib/SC68896 treatment reduces tumor mean vessel density and increases mean lumen area.

A) Representative histological tumor sections with CD31 vascular staining (brown) and hematoxylin nuclear counter stain (blue) from the four treatment groups. Microvessel examples are marked by arrows. B) MVD quantified from multiple CD31 stained sections for the four treatment groups, indicating a significantly lower level for cediranib/SC68896 versus untreated (pC) Mean lumen areas are indicated for the various treatment groups, with that for cediranib/SC68896 indicating a significantly higher level than untreated (p