RNA-Seq of livers of male C57/BL6N and Scly KO mice on diets containing 0.08 ppm (low) and 0.25 ppm (adequate) sodium selenite

We report the application of RNA sequencing technology for transcriptomic profiling in murine livers of male wild-type (WT) and Scly knockout (KO) mouse. This study provides a framework for combined metabolomics analysis of this mouse model lacking the capacity for selenocysteine decomposition. Overall design: 4 experimental groups: two genotypes fed two different diets containing low and medium sodium selenite concentrations