The proprotein convertase (PC) furin cleaves precursor proteins, an important step in the activation of many cancer-associated proteins. Substrates of furin and furin-like PCs play a role in prolifera
ABSTRACT The behavior of the tumor Doppler indexes and gene expression related to neovascularization was evaluated aiming to improve the characterization of neoplastic masses vascularization. Twenty-
a “−” presents a decrease in tumor size and “+” presents an increase in tumor sizes; more “+” marks indicate rapid growth.Three types in the balance of pro- and anti-angiogenesis.
