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SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells

Mendeley Data2021-03-19 更新2026-04-09 收录

肿瘤代谢调控

蛋白质琥珀酰化

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https://data.mendeley.com/datasets/5r2sxdtfpy 数据链接链接失效反馈

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资源简介：

Original Western blot data in association with MOLECULAR-CELL-D-19-00267R2

应用场景：

创建时间：

2021-03-19

肿瘤代谢调控

蛋白稳态

Mitochondria must buffer the risk of proteotoxic stress to preserve bioenergetics, but the role of these mechanisms in disease is poorly understood. Using a proteomics screen, we now show that the mit

Figshare2016-09-28 更新70

Additional file 7: Table S6. of The first succinylome profile of Trichophyton rubrum reveals lysine succinylation on proteins involved in various key cellular processes

蛋白质琥珀酰化

KEGG通路分析

KEGG enrichment analysis of the succinylated proteins. (XLSX 14Â kb)

Figshare2017-08-05 更新40

PD-1 instructs a tumor suppressive metabolic program to restrain AP-1 activity in T cell lymphoma

T细胞淋巴瘤机制

肿瘤代谢调控

To dissect T cell lymphoma pathogenesis, we previously engineered a genetically controllable murine model of human T-NHL based on tamoxifen-inducible irreversible expression of the T-NHL oncogene ITK-

NIAID Data Ecosystem30

eIF4GI Links Nutrient Sensing by mTOR to Cell Proliferation and Inhibition of Autophagy

肿瘤代谢调控

蛋白质翻译

Translation initiation factors have complex functions in cells which are not yet understood. We show that depletion of initiation factor eIF4GI only modestly reduces overall protein synthesis in cells

NIAID Data Ecosystem60

Oncogenic KRAS mediates amino acid metabolism during nutrient stress via regulation of NRF2 and ATF4 in NSCLC [shKRAS low Q]. Homo sapiens

肿瘤代谢调控

KRAS信号通路

Glutamine is a key nutrient for tumor cells that supports nucleotide and amino acid biosynthesis, replenishes the TCA cycle intermediates and contributes to redox metabolism. We identified oncogenic K

NIAID Data Ecosystem40

SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells

资源简介：

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