five

SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced genes

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NIAID Data Ecosystem2026-05-02 收录
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https://www.omicsdi.org/dataset/jpost/PXD047552
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资源简介:
Polycomb group (PcG) proteins are evolutionarily conserved repressors of developmental genes. Paradoxically, the same PcG proteins also play roles in gene activation via mechanisms that are not yet fully understood. Here, to reveal the function of S-phase kinase-associated protein 1A (SKP1A), an essential factor of SCF (SKP1A/CULLIN1/F-box) ubiquitin ligases, KDM2B interacting proteins were prepared by pull-down assays and characterized by LC-MS/MS
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2025-08-27
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