Simulated microgravity-induced changes in SUMOylation and protein expression in Saccharomyces cerevisiae

This study investigated the impact of simulated microgravity (SMG) on SUMOylation and protein expression in Saccharomyces cerevisiae. Utilizing a rotating wall vessel to simulate microgravity conditions, the research employed SILAC labeling and bottom-up proteomics to differentiate gravity vs SMG for SUMOylation (exp 1742) and for protein expression (exp 1772). N=6 for each experiment.